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Formula: C17H14N4O3S
SF-1670 (500 nM)–pretreated neutrophils show nearly 70% higher (maximal) superoxide production than untreated neutrophils
Chemical Name: 5-methoxy-3-(1
PubMed Central PMCID: PMC5227137
JX06 (40-80 mg/kg
SB-269970 Hydrochloride - CAS# 261901-57-9 Size:Solid 2 mg Formula: C17H14N4O3SSB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 261901
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